Big Ten Conference
Unsurprisingly, the Buckeyes have the upper hand against the Aggies. Ohio State is one of the greatest perennial powerhouses in collegiate football history and they have, sadly, demolished Texas A&M along the way.
In 1999, the Buckeyes defeated Texas A&M 24-14 in the Sugar Bowl.
Another perennial program the Aggies have never taken down, that has made its way to the Big Ten conference, is USC. The Trojans are 3-0 against Texas A&M, with their most recent win coming in 1977 in the Bluebonnet Bowl.
The Boilermakers defeated the Aggies 57 years ago in a 4-point victory. Rubbing salt in the wound, the Texas A&M loss took place at Kyle Field and was just one of four losses for the Aggies that season.